Roma (probable): Alisson; Florenzi, Manolas, Fazio, Kolarov; Nainggolan, De Rossi, Strootman; El Shaarawy, Dzeko, Perotti
This is a Scudetto showdown, as Juve are currently in second place and the Giallorossi are fourth, but with a game in hand.
La Joya is expected to return and with him the 4-2-3-1 formation that had been abandoned in favour of 4-3-3.
Paulo Dybala and Mario Mandzukic should be back in the starting XI for Juventus, while Roma rely on Stephan El Shaarawy and Edin Dzeko.
Roma are missing Gregoire Defrel and Rick Karsdorp, but otherwise have a full squad to choose from.
Dybala was dropped for two Serie A rounds in a row and broke his goal drought in the Coppa Italia win over Genoa midweek.
Eusebio Di Francesco rarely strays from his beloved 4-3-3 system but, unlike mentor Zdenek Zeman, he makes sure the defence is solid.
El Shaarawy and Diego Perotti are expected to fla线上足球投注nk centre-forward Edin Dzeko, leaving Patrik Schick on the bench.
Juventus (probable): Szczesny; Barzagli, Benatia, Chiellini, Alex Sandro; Pjanic, Khedira; Cuadrado, Dybala, Mandzukic; Higuain
Mandzukic and 在线外围投注Juan Cuadrado have shaken off injuries, sending Douglas Costa and Federico Bernardeschi back to the bench.
In fact, they have the best defensive record in Serie A this season, while Juve are the most prolific in attack.
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Juventus could also push Andrea Barzagli to right-back, in effect a three-and-a-half-man defence, often used in the Champions League.
Max Allegri is keeping everyone guessing, as he is without Gigi Buffon, Mattia De Sciglio and Benedikt Howedes, so Wojciech Szczesny starts against his old club.
Alessandro Florenzi should get the right-back spot with Daniele De Rossi available again after suspension.